Kexuan Li

I am a statistician at Bristol Myers Squibb (BMS).

My research interests span asymptotic theory, nonparametric statistics, survival analysis, deep learning, clinical trials, and quantum computing.

My industry work includes statistical contributions to global regulatory submissions and approvals for tofersen (Qalsody) in SOD1-ALS (FDA) and deucravacitinib (Sotyktu) in psoriatic arthritis (FDA), as well as pivotal study readouts for cendakimab in eosinophilic esophagitis.

Selected Publications

Google Scholar

Statistical Methodology

  • Nonparametric Inference under B-bits Quantization.
    Kexuan Li, Ruiqi Liu, Ganggang Xu, and Zuofeng Shang.
    Journal of Machine Learning Research (JMLR), 2024. [Link]
  • Calibrating Multi-dimensional Complex ODE from Noisy Data via Deep Neural Networks.
    Kexuan Li, Fangfang Wang, Ruiqi Liu, Fan Yang, and Zuofeng Shang.
    Journal of Statistical Planning and Inference, 2024. [Link]
  • Expected Treatment Benefit Ranking in a Randomized Clinical Trial.
    Kexuan Li.
    Statistics in Biopharmaceutical Research (Submitted).
  • Semiparametric Regression for Spatial Data via Deep Learning.
    Kexuan Li, Jun Zhu, Anthony R. Ives, Volker C. Radeloff, and Fangfang Wang.
    Spatial Statistics, 2023. [Link]
  • Prespecifying the RMST Restriction Time Under Nonproportional Hazards.
    Kexuan Li.
    New England Journal of Statistics in Data Science (Submitted).
  • Deep Feature Screening: Feature Selection for Ultra High-Dimensional Data via Deep Neural Networks.
    Kexuan Li, Fangfang Wang, Lingli Yang, and Ruiqi Liu.
    Neurocomputing, 2023. [Link]
  • Adaptive Neural Regression near Additivity: Estimation and Honest Uncertainty.
    Kexuan Li and Weidong Ma.
    AISTATS (Submitted).
  • Variable Selection for Nonlinear Cox Regression Model via Deep Learning.
    Kexuan Li.
    International Journal of Statistics and Probability, 2023. [Link]
  • Deep Estimation of Varying Regression Effects with Vanishing Conditional Variation.
    Kexuan Li and Weidong Ma.
    AISTATS (Submitted).
  • Analytic Evaluation of the Fractional Moments for the Quasi-Stationary Distribution of the Shiryaev Martingale on an Interval.
    Kexuan Li, Aleksey S. Polunchenko, and Andrey Pepelyshev.
    Communications in Statistics – Simulation and Computation, 2021. [Link]
  • Worst-Case Win Ratios Under Partially Specified Outcome Hierarchies.
    Kexuan Li, Xue Fan, and Lingli Yang.
    Stat (Submitted). [Link]
  • On the Convergence Rate of the Quasi- to Stationary Distribution for the Shiryaev–Roberts Diffusion.
    Kexuan Li and Aleksey S. Polunchenko.
    Sequential Analysis, 2020. [Link]
  • Multivariate Rank-Based Analysis of Multiple Endpoints in Clinical Trials: A Global Test Approach.
    Kexuan Li, Lingli Yang, Shaofei Zhao, Susie Sinks, Luan Lin, and Peng Sun.
    New England Journal of Statistics in Data Science (Minor revision). [Link]
  • Choosing Confidence Intervals in Bioequivalence Studies: 100(1 − 2α)% and 100(1 − α)% Approaches.
    Kexuan Li, Susie Sinks, Peng Sun, and Lingli Yang.
    Asian Journal of Probability and Statistics, 2024. [Link]
  • A Deep Learning Model for Spatially Clustered Data via Differentiable Cluster Assignment.
    Kexuan Li and Weidong Ma.
    Manuscript, 2026. [Link]
  • Deep Learning for Efficient GWAS Feature Selection.
    Kexuan Li.
    Manuscript, 2023. [Link]
  • Detection of LUAD-Associated Genes Using Wasserstein Distance in Multiomics Feature Selection.
    Shaofei Zhao, Siming Huang, Lingli Yang, Weiyu Zhou, Kexuan Li, and Shige Wang.
    Bioengineering, 2025. [Link]
  • Estimation and Hypothesis Testing of Derivatives in Smoothing Spline ANOVA Models.
    Ruiqi Liu, Kexuan Li, and Meng Li.
    Journal of the American Statistical Association (Submitted). [Link]
  • A Computationally Efficient Classification Algorithm in Posterior Drift Model: Phase Transition and Minimax Adaptivity.
    Ruiqi Liu, Kexuan Li, and Zuofeng Shang.
    Bernoulli (Submitted). [Link]
  • High-Dimensional Mean Testing with External Covariance Information.
    Xiang Wang and Kexuan Li.
    Journal of Multivariate Analysis (Submitted).
  • Inference-Preserving Coresets for Smooth M-Estimation.
    Xiang Wang and Kexuan Li.
    Statistics and Computing (Submitted).
  • Semiparametric Cox Regression with an Auxiliary Outcome.
    Xiang Wang, Kexuan Li, and Weidong Ma.
    Biometrics (Submitted).
  • Pattern-Based Sequential Multiple Imputation for Missing Data in Clinical Trials: An Extension for Baseline-Only Early Dropout Subjects.
    Chen Zhang, Junyu Nie, Kexuan Li, and Ning Ding.
    Pharmaceutical Statistics (Submitted). [Link]
  • Smoothly Weighted Win Statistics for Hierarchical Composite Endpoints.
    Xiang Wang, Kexuan Li, Lingli Yang, Xue Fan, Shaofei Zhao, and Weiyu Zhou.
    Manuscript.

Physics and Quantum Computing

  • Finite-Size Distribution Theory for Shallow Quantum Optimization Algorithms on Random Regular Graphs: Poisson Cycle Corrections and Gaussian Shot Noise.
    Kexuan Li.
    Physica Scripta (Submitted).

Clinical Trial Collaborations

Journal Articles

  • Cendakimab in Adults and Adolescents with Eosinophilic Esophagitis.
    Evan S. Dellon, …, Kexuan Li, …, Alain Schoepfer.
    NEJM Evidence, 2025. [Link]
    Full author list

    Evan S. Dellon, Christina M. Charriez, Sandra Zhang, Gary W. Falk, Salvatore Oliva, Christopher Ma, Jesse Siffledeen, Shauna Schroeder, Hamish Philpott, Tim Vanuytsel, Yasuhiko Abe, Kexuan Li, Carla L. Zema, Ashwini Venkatasamy, Anusha K. Yeshokumar, Young S. Oh, and Alain Schoepfer.

  • Pharmacokinetics and Pharmacodynamics of Natalizumab 6-Week Dosing vs Continued 4-Week Dosing for Relapsing-Remitting Multiple Sclerosis.
    John F. Foley, …, Kexuan Li, …, Tyler Lasky.
    Neurology: Neuroimmunology & Neuroinflammation, 2024. [Link]
    Full author list

    John F. Foley, Gilles Defer, Lana Zhovtis Ryerson, Jeffrey A. Cohen, Douglas L. Arnold, Helmut Butzkueven, Gary R. Cutter, Gavin Giovannoni, Joep Killestein, Heinz Wiendl, Kexuan Li, Liesel Dsilva, Marie Toukam, Kyle Ferber, Jihee Sohn, Holly Engelman, and Tyler Lasky.

Conference Abstracts and Presentations

  • Impact of Deucravacitinib on Disease Activity in Patients With Psoriatic Arthritis (PsA): Results From the Pivotal Phase 3 PsA Studies.
    Atul Deodhar, …, Kexuan Li, …, Philip J. Mease.
    ACR Convergence, 2025. Abstract 0874. Arthritis & Rheumatology, 77 (Supplement 9). [Link]
    Full author list

    Atul Deodhar, Ricardo Blanco, Arthur Kavanaugh, Alice Gottlieb, Laura Coates, Christopher Ritchlin, Alan Kivitz, Xiaofeng Zeng, Akimichi Morita, Diamant Thaçi, Stefan Varga, Kexuan Li, Ying-Ming Jou, Eleni Vritzali, and Philip J. Mease.

  • Cendakimab Efficacy and Safety in Adult and Adolescent Patients With Eosinophilic Esophagitis: 48-Week Results From the Randomized, Placebo-Controlled, Phase 3 Study.
    Evan S. Dellon, …, Kexuan Li, …, Alain Schoepfer.
    ACG Annual Scientific Meeting, 2024. Late-breaking abstract 43; oral presentation. [Link]
    Full author list

    Evan S. Dellon, Christina M. Charriez, Sandra Zhang, Gary Falk, Salvatore Oliva, Christopher Ma, Jesse Siffledeen, Shauna Schroeder, Hamish Philpott, Tim Vanuytsel, Christel Contzen, Yasuhiko Abe, Kexuan Li, Carla L. Zema, Ashwini Venkatasamy, Anusha Yeshokumar, Young S. Oh, and Alain Schoepfer.

  • Cendakimab Efficacy and Safety in Adult and Adolescent Patients With Eosinophilic Esophagitis: 24-Week Results From the Randomized, Placebo-Controlled, Phase 3 Study.
    Alain M. Schoepfer, …, Kexuan Li, …, Evan S. Dellon.
    UEG Week Vienna, 2024. Late-breaking abstract. United European Gastroenterology Journal, 12 (Supplement 8). [Link]
    Full author list

    Alain M. Schoepfer, Christina Charriez, Sandra Zhang, Gary Falk, Salvatore Oliva, Christopher Ma, Jesse Siffledeen, Shauna Schroeder, Hamish Philpott, Tim Vanuytsel, Christel Contzen, Yasuhiko Abe, Kexuan Li, Carla L. Zema, Ashwini Venkatasamy, Anusha Yeshokumar, Young S. Oh, and Evan S. Dellon.